Anti-LHX1 antibodies are used in the immunodetection of the protein LIM homeobox 1. In humans, the canonical protein has a reported length of 406 amino acid residues and a mass of 44.8 kDa. Its subcellular localization is in the nucleus. It is reported to be expressed in the brain, thymus, and tonsils. LHX1 is known to be involved with the morphogenesis of anatomical structure and organ morphogenesis.
The LHX1 marker can be used to identify Midbrain Splatter Neurons, Brain Splatter Neurons, Gray Matter Splatter Neurons, and Retina Horizontal Cells.* Synonyms for this target antigen include LIM1, LIM/homeobox protein Lhx1, LIM homeobox protein 1, homeobox protein Lim-1, and LIM-1. LHX1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of LHX1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Flow Cytometry, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4