PLEKHG5 is a symbol for the gene, Pleckstrin homology and RhoGEF domain containing G5, in humans. Other names include: Pleckstrin homology domain-containing family G member 5; PH domain-containing family G member 5; Guanine nucleotide exchange factor 720; GEF720; synectin-binding guanine exchange factor; CMTRIC; DSMA4; Syx; Tech; pleckstrin homology domain containing, family G (with RhoGef domain) member 5. The encoded protein has an amino acid length of 1062 and a mass of 117.5 kDa. Other isoforms may exist. This gene shares homology with other species, including: Mouse, Rat, Zebrafish, Frog, Chicken.