Anti-HIPK1 antibodies are used in the immunodetection of the protein homeodomain interacting protein kinase 1. In humans, the canonical protein has a reported length of 1210 amino acid residues and a mass of 130.8 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the CMGC Ser/Thr protein kinase protein family, HIPK1 is known to be a protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Post-translational modifications have been described, including sumoylation and phosphorylation. Synonyms for this target antigen include nuclear body associated kinase 2b, nuclear body-associated kinase 2, and homeodomain interacting protein kinase 1-like protein. HIPK1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some HIPK1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.