Anti-PTK2 antibodies are used in the immunodetection of the protein protein tyrosine kinase 2. In humans, the canonical protein has a reported length of 1052 amino acid residues and a mass of 119.2 kDa. Up to 7 different isoforms have been reported for this protein. It is notably expressed in B and T-lymphocytes. A member of the Tyr protein kinase protein family, PTK2 is known to be involved with angiogenesis and axon guidance. Post-translational modifications have been described, including sumoylation and phosphorylation. Synonyms for this target antigen include FADK 1, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, and FADK. PTK2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 2700 citations in the literature describe the use of PTK2 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.