Anti-ATP2B4 antibodies are used in the immunodetection of the protein ATPase plasma membrane Ca2+ transporting 4. In humans, the canonical protein has a reported length of 1241 amino acid residues and a mass of 137.9 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 8 different isoforms for this protein. A member of the Cation transport ATPase (P-type) (TC 3.A.3) protein family, it is known to be involved with brain development and the regulation of intracellular calcium. Synonyms for this target antigen include MXRA1, PMCA4, PMCA4b, PMCA4x, plasma membrane calcium-transporting ATPase 4, and ATP2B2.