Anti-immunoglobulin heavy constant alpha 2 (A2m marker) antibodies are used for the immunodetection of the protein encoded by the IGHA2 gene. In humans, the canonical protein has a reported length of 391 amino acid residues and a mass of 42.3 kDa. Its subcellular localization is in the cell membrane and is secreted. Alternative splicing is reported to yield 2 different isoforms for this protein. It is noted to be involved in adaptive immune responses. Post-translational modifications have been described, including glycosylation. Over 110 citations in the literature describe the use of immunoglobulin heavy constant alpha 2 (A2m marker) antibodies in research. ELISA is a widely used application for these antibodies. Flow Cytometry and Immunohistochemistry are also common applications.