Anti-WUCAM antibodies enable researchers to detect and measure the WUCAM antigen in biological samples. This target is a reported synonym of the TIGIT gene, which encodes T cell immunoreceptor with Ig and ITIM domains. This protein is known to bind with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. The human version of WUCAM has a canonical amino acid length of 244 residues and a protein mass of 26.3 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the cell membrane of cells. Indicated applications for WUCAM antibodies listed below include ELISA, Western Blot, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry.