TRPP1, or Polycystic kidney disease 1 (autosomal dominant), is a human gene encoded by PKD1. It may also be known as: Polycystin-1; Autosomal dominant polycystic kidney disease 1 protein; polycystin 1; transient receptor potential cation channel, subfamily P, member 1; PBP. The encoded protein has an amino acid length of 4303 and a mass of 462.5 kDa. Other isoforms may exist. TRPP1 is a member of the Polycystin family. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish, Frog, Chicken.