Anti-SmgGDS antibodies are used in antigen-specific immunodetection in biological samples. The target SmgGDS is a known alias name of the protein Rap1 GTPase-GDP dissociation stimulator 1, encoded by the RAP1GDS1 gene in humans. This 607-amino acid residue protein is known to act as a GEF (guanine nucleotide exchange factor) for the Rho family of small GTP-binding proteins (G proteins) that stimulates the dissociation of GDP to enable subsequent binding of GTP. It is localized to the nucleus, mitochondria, ER, and cytoplasm of the cell. It is reported to be widely expressed in many tissue types. Indicated applications for SmgGDS antibodies listed below include ELISA, Western Blot, and Immunohistochemistry.