Anti-PXR2 antibodies enable researchers to detect and measure the PXR2 antigen in biological samples. This target is a reported synonym of the PEX5L gene, which encodes peroxisomal biogenesis factor 5 like. This protein is reported to be an accessory subunit hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. The human version of PXR2 has a canonical amino acid length of 626 residues and a protein mass of 69.7 kilodaltons, although 8 isoforms have been identified. It is reported to be localized in the membrane and cytoplasm of cells and notably expressed in many tissues, such as the caudate and cerebral cortex. PXR2 is a member of the Peroxisomal targeting signal receptor protein family.