Anti-PPP1R17 antibodies are used in the immunodetection of the protein protein phosphatase 1 regulatory subunit 17. In humans, the canonical protein has a reported length of 155 amino acid residues and a mass of 17.9 kDa. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in cerebellum. PPP1R17 is reported to inhibit phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes. Post-translational modifications have been described, including phosphorylation.
The PPP1R17 marker can be used to identify Hypothalamus Splatter Neurons.* Synonyms for this target antigen include GSBS, G-substrate, and C7orf16. PPP1R17 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PPP1R17 antibodies have been mentioned in research publications and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.
*HuBMAP Human Reference Atlas v1.4