Anti-MYZAP antibodies are used in the immunodetection of the protein myocardial zonula adherens protein. In humans, the canonical protein has a reported length of 466 amino acid residues and a mass of 54.2 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 11 different isoforms have been reported for this protein. It is notably expressed in fetal liver, skeletal muscle, placenta, small intestine, lung, prostate and testis. A member of the MYZAP protein family, Myzap is reported to play a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF (By similarity). Synonyms for this target antigen include GRINL1A upstream protein, myocardial intercalated disc protein, myocardium-enriched ZO1-associated protein, myocardium-enriched zonula adherens protein, and GRINL1A complex locus upstream. MYZAP gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Western Blot is the most common application for the Myzap antibodies listed below. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.