Anti-NPL2 antibodies enable researchers to detect and measure the NPL2 antigen in biological samples. This target is a reported synonym of the HOGA1 gene, which encodes 4-hydroxy-2-oxoglutarate aldolase 1. This protein is known to function in metabolic processes, among other biological roles. The human version of NPL2 has a canonical amino acid length of 327 residues and a protein mass of 35.2 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the mitochondria of cells and notably expressed in many tissues, such as the gallbladder and kidney. NPL2 is a member of the DapA protein family.