Anti-NOD12 antibodies are used in antigen-specific immunodetection in biological samples. The target NOD12 is a known alias name of the protein NLR family pyrin domain containing 7, encoded by the NLRP7 gene in humans. This 980-amino acid residue protein is reported to inhibit CASP1/caspase-1-dependent IL1B secretion. In terms of tissue expression, it is reported to be expressed in numerous tissues including uterus and ovary, with low levels in the heart and brain.