Anti-HS2 antibodies enable researchers to detect and measure the HS2 antigen in biological samples. This target is a reported synonym of the SPTB gene, which encodes spectrin beta, erythrocytic. This protein is known to function in cytoskeleton organization, among other biological roles. The human version of HS2 has a canonical amino acid length of 2137 residues and a protein mass of 246.5 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the cytoplasm of cells and notably expressed in many tissues, such as the bone marrow and cerebellum. This target antigen may also be known as EL3.