Anti-Cofilin 1 antibodies are used for the immunodetection of the protein encoded by the CFL1 gene. In humans, the canonical protein has a reported length of 166 amino acid residues and a mass of 18.5 kDa. It is reported to be widely expressed in various tissues. A member of the Actin-binding proteins ADF protein family, it is known to bind to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include HEL-S-15, cofilin, 18 kDa phosphoprotein, cofilin 1 (non-muscle), epididymis secretory protein Li 15, p18, and CFL. Gene orthologs have been identified in the mouse, rat, bovine, frog and chimpanzee species. Over 980 citations in the literature describe the use of Cofilin 1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.