Anti-EMC4 antibodies are used in the immunodetection of the protein ER membrane protein complex subunit 4. In humans, the canonical protein has a reported length of 183 amino acid residues and a mass of 20.1 kDa. Its subcellular localization is in the ER. Up to 3 different isoforms have been reported for this protein. It is notably expressed in the colon, cerebral cortex, cerebellum, caudate, and adrenal gland. A member of the EMC4 protein family, EMC4 is known to be a part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Synonyms for this target antigen include TMEM85, cell proliferation-inducing gene 17 protein, transmembrane protein 85, and PIG17. EMC4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. A number of EMC4 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, and Immunofluorescence are also common applications.