Anti-ERVFRD-1 antibodies are used in the immunodetection of the protein endogenous retrovirus group FRD member 1, envelope. In humans, the canonical protein has a reported length of 538 amino acid residues and a mass of 59.5 kDa. Its subcellular localization is in the cell membrane. It is noted to be expressed at higher level in the placenta. It is a member of the Gamma type-C retroviral envelope protein family. Post-translational modifications have been described, including protein cleavage and glycosylation. Synonyms for this target antigen include HERV-FRD provirus ancestral Env polyprotein, HERV-FRD_6p24.1 provirus ancestral Env polyprotein, endogenous retrovirus group FRD, member 1, envelope polyprotein, syncytin 2, and syncytin-2. ERVFRD-1 gene orthologs have been reported in the mouse and chimpanzee species. A number of ERVFRD-1 antibodies have been mentioned in research publications and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.