Anti-ETB antibodies are protein reagents that detect specific antigens. The ETB antigen is another term for the human protein endothelin receptor type B, encoded by the EDNRB gene. The protein is known to function in pathways of aging and the Wnt signaling pathway, among other biological roles. Canonically, it has an amino acid length of 442 residues and a mass of 49.6 kilodaltons. Its subcellular localization is in the cell membrane and it is reported to be expressed in the placental stem villi vessels, but not in cultured placental villi smooth muscle cells. The ETB protein is a member of the G-protein coupled receptor 1 protein family. Other alias names for ETB include ABCDS and ET-BR. Some ETB antibodies may have been used in research and have associated citations. Immunohistochemistry is a widely used application for these antibodies. In addition, Western Blot is also a common application.