Anti-checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase antibodies enable researchers to detect and measure the checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase antigen in biological samples. This target is a reported synonym of the CHFR gene, which encodes checkpoint with forkhead and ring finger domains. This protein is known to function in cell division and protein ubiquitination, among other biological roles. The human version of checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase has a canonical amino acid length of 664 residues and a protein mass of 73.4 kilodaltons, although 5 isoforms have been identified. It is reported to be localized in the nucleus of cells and notably expressed in many tissues, such as the gallbladder and seminal vesicle. Other names for this target antigen include E3 ubiquitin-protein ligase CHFR, RING finger protein 196, and RING-type E3 ubiquitin transferase CHFR.