Anti-AP5Z1 antibodies are used in the immunodetection of the protein adaptor related protein complex 5 subunit zeta 1. In humans, the canonical protein has a reported length of 807 amino acid residues and a mass of 88.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. AP5Z1 is known to be involved with DNA repair and protein transport. The AP5Z1 gene has been associated with the disease, Spastic paraplegia. Synonyms for this target antigen include SPG48, zeta, AP-5 complex subunit zeta-1, adapter-related protein complex 5 zeta subunit, adaptor related protein complex 5 zeta 1 subunit, and KIAA0415. AP5Z1 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Some AP5Z1 antibodies may have been used in research and have associated citations. Immunohistochemistry is a widely used application for these antibodies. Western Blot and Immunofluorescence are also common applications.