Anti-Acid Phosphatase 3 antibodies are used for the immunodetection of the protein encoded by the ACP3 gene. In humans, the canonical protein has a reported length of 386 amino acid residues and a mass of 44.6 kDa. Its subcellular localization is in the cell membrane, nucleus, lysosomes, cytoplasm, and is secreted. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be highly expressed in the prostate, restricted to glandular and ductal epithelial cells. A member of the Histidine acid phosphatase protein family, it is known to be involved with the metabolism of lipids. Post-translational modifications have been described, including N-glycosylation and protein cleavage. Other names for this target antigen include ACPP, TM-PAP, prostatic acid phosphatase, TMPase, acid phosphatase, prostate, and 5'-NT. Gene orthologs have been identified in the mouse, rat, bovine, frog and chimpanzee species.