Anti-One Cut Homeobox 2 antibodies are used for the immunodetection of the protein encoded by the ONECUT2 gene. In humans, the canonical protein has a reported length of 504 amino acid residues and a mass of 54.3 kDa. Its subcellular localization is in the nucleus. A member of the CUT homeobox protein family, it is known to be a type of transcriptional activator.
The one cut homeobox 2 marker can be used to characterize Eccentric Medium Spiny Neurons, Hypothalamus Mammillary Body Neurons, Retina Horizontal Cells, and Ventral Excitatory Neurons.* Other names for this target antigen include OC2, one cut domain family member 2, HNF-6-beta, ONECUT-2 homeodomain transcription factor, hepatocyte nuclear factor 6-beta, and OC-2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of One Cut Homeobox 2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4