Anti-NKG2E antibodies enable researchers to detect and measure the NKG2E antigen in biological samples. This target is a reported synonym of the KLRC3 gene, which encodes killer cell lectin like receptor C3. This protein is reported to play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The human version of NKG2E has a canonical amino acid length of 240 residues and a protein mass of 27.1 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the membrane of cells and notably expressed in the tonsil.