Anti-RFWD3 antibodies are used in the immunodetection of the protein ring finger and WD repeat domain 3. In humans, the canonical protein has a reported length of 774 amino acid residues and a mass of 85.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. Among its functions, RFWD3 is involved with DNA damage pathways and DNA repair. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include RNF201, E3 ubiquitin-protein ligase RFWD3, RING finger and WD repeat domain-containing protein 3, RING finger protein 201, RING-type E3 ubiquitin transferase RFWD3, and FANCW.