Anti-PPP1CA antibodies are used in the immunodetection of the protein protein phosphatase 1 catalytic subunit alpha. In humans, the canonical protein has a reported length of 330 amino acid residues and a mass of 37.5 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the PPP phosphatase protein family, PPP1CA is reported to be a protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Synonyms for this target antigen include PP1A, PP1alpha, PPP1A, serine/threonine-protein phosphatase PP1-alpha catalytic subunit, and PP-1A. PPP1CA gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 190 citations in the literature describe the use of PPP1CA antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.