Anti-DNA polymerase eta antibodies are used for the immunodetection of the protein encoded by the POLH gene. In humans, the canonical protein has a reported length of 713 amino acid residues and a mass of 78.4 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the DNA polymerase type-Y protein family, it is known to be involved with DNA repair and DNA replication. Post-translational modifications have been described, including ubiquitination. Other names for this target antigen include RAD30A, XP-V, XPV, DNA polymerase eta transcript, RAD30 homolog A, and RAD30. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of DNA polymerase eta antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.