Anti-ROS1 antibodies are used in the immunodetection of the protein ROS proto-oncogene 1, receptor tyrosine kinase. In humans, the canonical protein has a reported length of 2347 amino acid residues and a mass of 263.9 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in the brain. A member of the Tyr protein kinase protein family, ROS1 is known to be involved with cell differentiation and protein phosphorylation. Post-translational modifications have been described, including phosphorylation and glycosylation. Synonyms for this target antigen include ROS, c-ros-1, proto-oncogene tyrosine-protein kinase ROS, c-ros oncogene 1 , receptor tyrosine kinase, and MCF3. ROS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.