Anti-DNA polymerase kappa antibodies are used for the immunodetection of the protein encoded by the POLK gene. In humans, the canonical protein has a reported length of 870 amino acid residues and a mass of 98.8 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 8 different isoforms for this protein. A member of the DNA polymerase type-Y protein family, it is known to be involved with DNA damage pathways and DNA repair. Other names for this target antigen include DINP, POLQ, polymerase (DNA directed) kappa, and DINB1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of DNA polymerase kappa antibodies have been mentioned in research publications and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.