Anti-ceramide synthase 2 antibodies are used for the immunodetection of the protein encoded by the CERS2 gene. In humans, the canonical protein has a reported length of 380 amino acid residues and a mass of 44.9 kDa. Its subcellular localization is in the ER. It is reported to be expressed in the kidney, liver, brain, heart, placenta and lung. It is reported to be a ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very-long-chain fatty acyl-CoA (chain length C22-C27). Post-translational modifications have been described, including glycosylation, acetylation and phosphorylation. Other names for this target antigen include LASS2, SP260, TMSG1, LAG1 homolog, ceramide synthase 2, LAG1 longevity assurance 2, and L3. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of ceramide synthase 2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.