Anti-THRA antibodies are used in the immunodetection of the protein thyroid hormone receptor alpha. In humans, the canonical protein has a reported length of 490 amino acid residues and a mass of 54.8 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Nuclear hormone receptor protein family, THRA is known to be involved with the differentiation of certain cell types. The THRA gene has been associated with the disease, Hypothyroidism. Synonyms for this target antigen include CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, and AR7. THRA gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 90 citations in the literature describe the use of THRA antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.