Anti-PIP3E antibodies enable researchers to detect and measure the PIP3E antigen in biological samples. This target is a reported synonym of the IPCEF1 gene, which encodes interaction protein for cytohesin exchange factors 1. This protein is known to function in the response to oxidative stress, among other biological roles. The human version of PIP3E has a canonical amino acid length of 437 residues and a protein mass of 49 kilodaltons, although 5 isoforms have been identified. It is reported to be localized in the cell membrane and cytoplasm of cells and notably expressed in many tissues, such as the bone marrow, tonsil, and appendix.