Anti-Phospholipase D1 antibodies are used for the immunodetection of the protein encoded by the PLD1 gene. In humans, the canonical protein has a reported length of 1074 amino acid residues and a mass of 124.2 kDa. Its subcellular localization is in the ER, Golgi, and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is noted to be expressed abundantly in the pancreas and heart and at high levels in the brain, placenta, spleen, uterus and small intestine. A member of the Phospholipase D protein family, it is known to be involved with chemotaxis and the metabolism of lipids. The gene encoding this protein is implicated in Cardiac valvular dysplasia. Other names for this target antigen include CVDP1, choline phosphatase 1, phosphatidylcholine-hydrolyzing phospholipase D1, phospholipase D1, phosphatidylcholine-specific, and CVDD. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.