Anti-Myoferlin antibodies are used in the immunodetection of the protein encoded by the MYOF gene. In humans, the canonical protein has a reported length of 2061 amino acid residues and a mass of 234.7 kDa. Its subcellular localization is in the nucleus, cytoplasmic vesicles, and cell membrane. Alternative splicing is reported to yield 8 different isoforms for this protein. It is reported to be expressed in myoblast and endothelial cells. A member of the Ferlin protein family, it is reported to be a calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Other names for this target antigen include HAE7, fer-1-like 3, myoferlin, fer-1-like family member 3, fer-1-like protein 3, and FER1L3.