Anti-Activation-Induced Cytidine Deaminase antibodies are used in the immunodetection of the protein encoded by the AICDA gene. In humans, the canonical protein has a reported length of 198 amino acid residues and a mass of 24 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be highly expressed in lymph nodes and tonsils. A member of the Cytidine and deoxycytidylate deaminase protein family, it is known to be involved with B cell differentiation and the cellular response to lipopolysaccharides. Post-translational modifications have been described, including ubiquitination and phosphorylation. Other names for this target antigen include cytidine aminohydrolase, epididymis secretory protein Li 284, integrated into Burkitt's lymphoma cell line Ramos, and single-stranded DNA cytosine deaminase.