Anti-BRIP1 antibodies are used in the immunodetection of the protein BRCA1 interacting helicase 1. In humans, the canonical protein has a reported length of 1249 amino acid residues and a mass of 140.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is widely expressed across many tissue types. A member of the DEAD box helicase protein family, it is known to be involved with the cellular response to hypoxia and DNA damage pathways. Post-translational modifications have been described, including acetylation and phosphorylation. Synonyms for this target antigen include ATP-dependent RNA helicase BRIP1, BRCA1 interacting protein C-terminal helicase 1, BRCA1-associated C-terminal helicase 1, BRCA1-binding helicase-like protein BACH1, and Fanconi anemia group J protein.