Anti-mGluR5 antibodies enable researchers to detect and measure the mGluR5 antigen in biological samples. This target is a reported synonym of the GRM5 gene, which encodes glutamate metabotropic receptor 5. This protein is known to function in chemical synaptic transmission and MAPK cascade signaling pathways, among other biological roles. The human version of mGluR5 has a canonical amino acid length of 1212 residues and a protein mass of 132.5 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the cell membrane of cells. Other names for this target antigen include GPRC1E and PPP1R86. Immunohistochemistry is a widely used application for the mGluR5 antibodies listed below. In addition, Western Blot is also a common application.