Anti-Semaphorin 3F antibodies are used in the immunodetection of the protein encoded by the SEMA3F gene. In humans, the canonical protein has a reported length of 785 amino acid residues and a mass of 88.4 kDa. It is known to be a secreted protein. Alternative splicing is reported to yield 2 different isoforms for this protein. It is noted to be expressed abundantly but differentially in a variety of neural and nonneural tissues. A member of the Semaphorin protein family, it is believed to play a role in cell motility and cell adhesion. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include SEMA4, SEMAK, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F, and SEMA-IV.