Anti-PRND antibodies are used in the immunodetection of the protein prion like protein doppel. In humans, the canonical protein has a reported length of 176 amino acid residues and a mass of 20.3 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in the testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid. A member of the Prion protein family, PRND is reported to be required for normal acrosome reaction and for normal male fertility (By similarity). Post-translational modifications have been described, including O-glycosylation and N-glycosylation. Synonyms for this target antigen include DPL, PrPLP, dJ1068H6.4, downstream prion protein-like, prion gene complex, downstream, and DOPPEL. PRND gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Western Blot is the most common application for the PRND antibodies listed below. ELISA and Immunohistochemistry are also common applications.