Anti-CYP46A1 antibodies are used in the immunodetection of the protein cytochrome P450 family 46 subfamily A member 1. In humans, the canonical protein has a reported length of 500 amino acid residues and a mass of 56.8 kDa. Its subcellular localization is in the ER. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be expressed in the brain. A member of a the Cytochrome P450 protein family, CYP46A1 is reported to be a P450 monooxygenase that plays a major role in cholesterol homeostasis in the brain. Synonyms for this target antigen include CYP46, cholesterol 24-hydroxylase, CH24H, cholesterol 24-monooxygenase, cholesterol 24S-hydroxylase, and CP46.