Anti-Lamin B2 antibodies are used for the immunodetection of the protein encoded by the LMNB2 gene. In humans, the canonical protein has a reported length of 620 amino acid residues and a mass of 69.9 kDa. Its subcellular localization is in the nucleus. It is a member of the Intermediate filament protein family. Post-translational modifications have been described, including phosphorylation. The gene encoding this protein is implicated in Partial acquired lipodystrophy. Other names for this target antigen include epididymis secretory sperm binding protein and lamin B3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 140 citations in the literature describe the use of Lamin B2 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.