Anti-POU2F1 antibodies are used in the immunodetection of the protein POU class 2 homeobox 1. In humans, the canonical protein has a reported length of 743 amino acid residues and a mass of 76.5 kDa. Its subcellular localization is in the nucleus. Up to 6 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the POU transcription factor protein family, POU2F1 is reported to be a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Synonyms for this target antigen include OTF1, Oct1Z, oct-1B, POU domain, class 2, transcription factor 1, NF-A1, and OCT1. POU2F1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 70 citations in the literature describe the use of POU2F1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.