Anti-MACROD2 antibodies are used in the immunodetection of the protein mono-ADP ribosylhydrolase 2. In humans, the canonical protein has a reported length of 425 amino acid residues and a mass of 47.4 kDa. Its subcellular localization is in the nucleus. Up to 5 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. MACROD2 is known to be involved with brain development and DNA damage pathways. Synonyms for this target antigen include MACRO domain containing 2, MACRO domain-containing protein 2, O-acetyl-ADP-ribose deacetylase MACROD2, [Protein ADP-ribosylaspartate] hydrolase MACROD2, and ADP-ribose glycohydrolase MACROD2. MACROD2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are common applications for MACROD2 antibodies.