Anti-Hyaluronidase 3 antibodies are used for the immunodetection of the protein encoded by the HYAL3 gene. In humans, the canonical protein has a reported length of 417 amino acid residues and a mass of 46.5 kDa. Its subcellular localization is in the cytoplasmic vesicles, ER, cell membrane, and is secreted. Alternative splicing is reported to yield 4 different isoforms for this protein. It is notably expressed in sperm. A member of the Glycosyl hydrolase 56 protein family, it is known to be involved with carbohydrate metabolism and homeostasis and cartilage development. Other names for this target antigen include LUCA3, hyaluronoglucosaminidase 3, lung carcinoma protein 3, and LUCA-3. Gene orthologs have been identified in the mouse, rat, bovine, chimpanzee and chicken species. Some Hyaluronidase 3 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.