Anti-KISS1R antibodies are used in the immunodetection of the protein KISS1 receptor. In humans, the canonical protein has a reported length of 398 amino acid residues and a mass of 42.6 kDa. Its subcellular localization is in the cell membrane. It is notably widely expressed in many tissue types. A member of the G-protein coupled receptor 1 protein family, KISS1R is a known receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. Post-translational modifications have been described, including glycosylation. The KISS1R gene has been associated with the disease, Hypogonadotropic hypogonadism 8 with or without anosmia. Synonyms for this target antigen include G-protein coupled receptor OT7T175, hypogonadotropin-1, kisspeptins receptor, metastin receptor, and G protein-coupled receptor 54. KISS1R gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. Over 50 citations in the literature describe the use of KISS1R antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.