Anti-adenylate cyclase 9 antibodies are used in the immunodetection of the protein encoded by the ADCY9 gene. In humans, the canonical protein has a reported length of 1353 amino acid residues and a mass of 150.7 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in skeletal muscle, pancreas, lung, heart, kidney, liver, brain and placenta. A member of the Adenylyl cyclase class-4/guanylyl cyclase protein family, it is reported to be an adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include ACIX, adenylate cyclase type 9, ATP pyrophosphate-lyase 9, adenylate cyclase type IX, adenylyl cyclase 9, and AC9.