Anti-DOPA Decarboxylase antibodies are used for the immunodetection of the protein encoded by the DDC gene. In humans, the canonical protein has a reported length of 480 amino acid residues and a mass of 53.9 kDa. Alternative splicing is reported to yield 4 different isoforms for this protein. A member of the Group II decarboxylase protein family, it is known to catalyze the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin. The gene encoding this protein is implicated in Aromatic L-amino-acid decarboxylase deficiency. Other names for this target antigen include aromatic-L-amino-acid decarboxylase, dopa decarboxylase (aromatic L-amino acid decarboxylase), and AADC. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of DOPA Decarboxylase antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.