Anti-ANO5 antibodies are used in the immunodetection of the protein anoctamin 5. In humans, the canonical protein has a reported length of 913 amino acid residues and a mass of 107.2 kDa. Its subcellular localization is in the ER and cell membrane. It is reported to be highly expressed in the brain, heart, kidney, lung, and skeletal muscle. It is a member of the Anoctamin protein family. Post-translational modifications have been described, including glycosylation. The ANO5 gene has been associated with the disease, Gnathodiaphyseal dysplasia. Synonyms for this target antigen include integral membrane protein GDD1, transmembrane protein 16E, and gnathodiaphyseal dysplasia 1 protein. ANO5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some ANO5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.