Anti-C16orf92 antibodies are used in the immunodetection of the protein chromosome 16 open reading frame 92. In humans, the canonical protein has a reported length of 132 amino acid residues and a mass of 14.4 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is reported to have testis-specific expression. C16orf92 is believed to play a role in sperm-oocyte fusion during fertilization. Synonyms for this target antigen include fertilization-influencing membrane protein and uncharacterized protein C16orf92. C16orf92 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.