Anti-ATG16L2 antibodies are used in the immunodetection of the protein autophagy related 16 like 2. In humans, the canonical protein has a reported length of 619 amino acid residues and a mass of 69 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of a the WD repeat ATG16 protein family, ATG16L2 is believed to play a role in regulating epithelial homeostasis in an ATG16L1-dependent manner. Synonyms for this target antigen include APG16-like 2, ATG16 autophagy related 16-like 2, WD repeat-containing protein 80, autophagy-related protein 16-2, and protein Atg16l2.